Organised by Banbury Town Council in partnership with Banbury FM, the event will be free-to-enter and will feature five live music acts.
Food and drink stalls will provide on-site refreshments while town centre pubs, clubs, and restaurants will open as usual.
Starting the show, at around 6pm, will be guitarist/vocalist Leigh Chambers who will perform covers of 70s, 80s, 90s hits.
Next up will be Cold Blue Daze, a four-piece band that plays rock, classic rock and alternative music. The group is influenced by ZZ Top, Rolling Stones, Foo Fighters, Kings of Leon and others.
Three-piece band BushFieldSmith will play acoustic originals and covers with a reggae flavour.
Oxford group Seven O’Clock Junkies will perform rock/pop originals and covers of anything from REM to Elvis Costello.
Headlining will be The Meanies, a soul, Motown ska and 60s classics band who are firm favourites with Banbury-area audiences.
Banbury mayor John Colegrave said: “Last year’s Music Mix was a huge success and this year could be even better.
“There’s a great line-up of bands and no-one should go home disappointed. It will be another fabulous free event for townspeople.”
The event will run from 6pm until late on Friday, July 26.