Eddie Dancer, 13, of Croughton was given a standing ovation after performing in front of 600 people at the Mermaid Theatre, London.
The violinist, who has autism, was one of 23 acts from a number of countries, chosen during a rigorous audition process.
He joined singers, guitarists, dancers and magicians from as far afield as America, Croatia, Sweden and Canada in the show, Autism’s Got Talent.
Eddie said: “I already want to come back next year as I have proved to myself if I want to do something I can do it and do it well.”
Eddie was introduced to Strictly Come Dancing star Robin Windsor, friends with show organiser and autism campaigner Anna Kennedy, who was delighted to meet Eddie and was full of praise for his performance.
Robin said: “Eddie was absolutely fantastic tonight. It is so amazing what music and dance can do for people on the autism spectrum – it can really enhance their lives”.
The schoolboy was accompanied by his violin teacher Noriko Tsuzaku and his assistance dog Harmony. He played a rendition of The New Round O on his violin and passed the test to rapturous applause.
Eddie attends LVS Oxford, a school for children with a diagnosis on the autism spectrum. Teachers nominated him to play at Autism’s Got Talent having developed his confidence and encouraged his talent since he joined when the school opened in September 2014.
The show, in its fifth year, is a celebration of autism talent and with LVS Oxford’s ethos to develop its learners to have the confidence and skills to lead happy, independent lives it was natural to want Eddie to show his potential.
His mother Bev noted how far Eddie has come. She said: “Eddie is a lot calmer now and can achieve so much more at home too. At mainstream primary school we were just getting by day to day, but now he is so much more receptive as at LVS Oxford he is far more relaxed.
“He made a small mistake today which in the past would have been the end of the performance for Eddie but now he has the confidence and belief to overcome obstacles”.