Thames Valley Police officers responded to reports of a burglary in progress at a building site in Kingerlee Road last night.
Officers attended and gained entry to a vacant property.
A man inside the building had attempted to 'make off' by jumping out of a window, suffering injuries to his ankles.
Police arrested the 35-year-old man on suspicion of burglary and he was taken to hospital where he remained late today (Thursday March 25).
South Central Ambulance Service sent multiple resources to the incident.
An ambulance service spokesperson said: "The Thames Valley Air Ambulance was one of a number of resources we sent after a person had fallen from a building, sustaining serious leg injuries.
"After initial treatment at the scene, they were taken to the John Radcliffe Hospital in Oxford by road."