Style Acre will officially open its new Banbury hub on Friday which will support young adults with learning disabilities.
The building was formerly Le Royale nightclub in Butchers Row and had been left empty for many years.
But the charity has refurbished the three-storey complex, called SABRe (Style Acre Banbury Resource), to help between 60 and 80 adults learn new skills and find volunteering and job opportunities.
Construction work took about nine months to complete at a cost of £900,000. Facilities will include an IT suite, community room and apartments to house eight adults.
Attending the official opening on Friday will be BBC Countryfile presenter John Craven, who is a vice-patron of the charity.